If you've been searching for options beyond traditional antidepressants, you've probably come across two names: ketamine and Spravato. They're related, but they are not the same treatment. Here is a plain-language comparison to help you understand the differences and prepare questions for your provider. Although we don’t currently offer Spravato, we’re happy to discuss whether it may be a better fit for you. The short answer Spravato (esketamine) is an FDA-approved nasal spra

Science Daily (www.sciencedaily.com) presented details from a study published in Molecular Psychiatry on March 5, 2026. From the article: "Major depressive disorder (MDD) is a major global health problem and one of the leading causes of disability. About 30% of people diagnosed with depression develop treatment-resistant depression (TRD), meaning their symptoms do not improve sufficiently with standard antidepressant medications. Ketamine has gained attention as a fast-acting